Curcumin is a well-known dietary polyphenol derived from the rhizomes of turmeric, an Indian spice. The anticancer effect of curcumin has been demonstrated in many cell and animal studies, and recent research has shown that curcumin can target cancer stem cells (CSCs). CSCs are proposed to be responsible for initiating and maintaining cancer, and contribute to recurrence and drug resistance. A number of studies have suggested that curcumin has the potential to target CSCs through regulation of CSC self-renewal pathways. The potential impact of curcumin, alone or in combination with other anticancer agents on CSCs was evaluated as well. Furthermore, the safety and tolerability of curcumin have been well-established by numerous clinical studies. Importantly, the low bioavailability of curcumin has been dramatically improved through the use of structural analogues or special formulations. More clinical trials are underway to investigate the efficacy of this promising agent in cancer chemoprevention and therapy. In conclusion, curcumin could be a very promising adjunct to traditional cancer treatments.
This information is bought to you as a free service from DNA Biopharm South Africa. The information herein is not intended to treat or diagnose any condition. Should you wish to try any herbal or natural remedy discussed in these pages, please consult with your health care practitioner. Should you require any information or advice on any topic related to diabetes, please visit our website at www.dna-biopharm.com
This information is bought to you as a free service from DNA Biopharm South Africa. The information herein is not intended to treat or diagnose any condition. Should you wish to try any herbal or natural remedy discussed in these pages, please consult with your health care practitioner. Should you require any information or advice on any topic related to diabetes, please visit our website at www.dna-biopharm.com
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